For many people, starting an antidepressant is the first step toward feeling better. But what happens when that step doesn’t lead where you hoped?
If you’ve tried multiple medications without relief, you’re not alone. This is often referred to as treatment-resistant depression (TRD) and it’s more common than most people realize.
What Is Treatment-Resistant Depression?
Treatment-resistant depression typically means:
- You’ve tried two or more antidepressants
- Symptoms haven’t significantly improved
- You continue to feel stuck, exhausted, overwhelmed, or depressed
This can be frustrating—and discouraging. But it does not mean you’re out of options.
A Different Approach to Treatment
Advances in mental health care have introduced new approaches that work differently than traditional medications.
One of those options is Spravato® (esketamine) – an FDA-approved treatment designed specifically for adults with treatment-resistant depression.
How Spravato Is Different
Unlike standard antidepressants that can take weeks to build up in your system, Spravato works through a different pathway in the brain.
It is:
- Administered in a controlled, clinical setting
- Used alongside an oral antidepressant
- Designed for patients who haven’t responded to other treatments
What to Expect
At Arise Psychiatry, Spravato treatment is carefully monitored in-office to ensure safety and comfort.
Your care team will:
- Evaluate if you’re a candidate
- Walk you through the process
- Support you throughout your treatment journey
You Still Have Options
If you’ve been feeling like nothing is working, it’s easy to lose hope.
But the truth is mental health treatment is not one-size-fits-all.
There are still paths forward. And sometimes, the right treatment simply hasn’t been found yet.